Inside the World's Most Studied Saffron: Meet affron®

Let’s be real: modern life is a lot. Between the mental load of keeping everyone’s schedules straight, the doomscrolling before bed, the work stress, and the constant pressure to be "on," it’s no wonder women are feeling more overwhelmed than ever. In fact, 1 in 2 women say their stress levels have increased in the past five years (1). And here’s another fun fact (sarcasm fully intended): women are twice as likely to be diagnosed with anxiety compared to men (2).

It’s time we start talking more about what women need for mood and mental well-being—and start spotlighting ingredients that are actually backed by science. So today, we’re digging into one of the most promising (and powerful) botanicals in the mental wellness world:Saffron. Specifically, a patented form called affron® .

affron® is a premium, clinically studied saffron extract derived from the Crocus sativus L. flower. Yep, the same plant that gives us that golden-orange culinary spice is also a powerhouse when it comes to supporting mental well-being.

But here’s where affron® steps into its own lane: it’s not just any Saffron . It’s the most clinically backed and awarded Saffron ingredient in the world . With 9 published clinical studies , affron® has been shown to help reduce occasional anxiety and low mood, improve sleep quality, and even support energy levels (3)(4).

And it’s not just hype. Over 4 million people worldwide have benefited from affron® to help maintain a positive mood and emotional balance (5).

The mood and mental health supplement category is growing twice as fast as the supplement industry overall (6). That’s a big deal. Women are seeking more natural, non-habit-forming ways to help them navigate the stress, mood swings, and sleepless nights that come with the territory of modern womanhood.

Saffron has been used traditionally for centuries to support relaxation, but today’s science is showing us that Saffron is more than just a spice—it’s a serious contender for emotional and mental support.

Not all Saffron is created equal. In fact, many Saffron supplements on the market use low-grade extracts or blends that don’t guarantee consistent levels of active compounds. affron® is standardized to contain 3.5% Lepticrosalides™—the main bioactive compounds responsible for Saffron’s benefits (3).

Here’s what sets affron® apart (7):

• Most clinically studied Saffron ingredient worldwide

• Patented technology that ensures purity, consistency, and potency

• Proven bioavailability (aka, your body actually absorbs and uses it)

• High stability for reliable shelf life and performance

• Well-tolerated with no reported side effects in over 600 clinical participants

In a growing body of research, affron® has shown real, measurable benefits for emotional and mental well-being (5):

• 33% reduction in occasional anxiety symptoms
  

• 32% reduction in low mood and negative thoughts
  

• 20% increase in feeling more energized after waking
  

• Improved sleep quality in just 7 days
  
  

That last one is huge, considering how many women struggle with winding down at night or waking up feeling groggy.

And no, these weren’t just vague survey results. These were peer-reviewed, placebo-controlled clinical trials on real humans.

While affron® shines on its own, it really levels up when paired with other calming nutrients like Magnesium and L-Theanine . That’s exactly why we formulated Miss Bliss™ with all three.

• Magnesium is essential for hundreds of bodily functions, but it’s especially key for helping muscles (and minds) relax. It supports the nervous system, helps reduce restlessness, and promotes more restful sleep (8).*
  
  

• L-Theanine is a naturally occurring amino acid that promotes alpha brain waves—aka the relaxed, focused state your brain enters during meditation. It can help reduce tension and promote a sense of calm without making you drowsy (9).*

Together with affron®, these ingredients create a powerful trifecta of chill: support for your mood, your stress response, and your ability to truly rest and recharge.*

Let’s not forget: investing in your mental well-being isn’t just about getting through the hard days—it’s about thriving. affron® gives women a science-backed way to take charge of their mood and stress levels without turning to habit-forming options. It’s gentle enough for daily use and powerful enough to make a difference you can feel.

Whether you're juggling work deadlines, family obligations, or just trying to keep your head above water, you deserve solutions that honor your body and your brain. Mental wellness isn’t a luxury—it’s a necessity. And affron® is here to help make it a little more accessible, one feel-good day at a time.

We know supplements aren’t magic pills. But they can be powerful tools in your toolkit when life feels like a lot (because, again, it is).

If you’re tired of lying awake with your brain racing, or you just want to stop feeling like you’re running on edge all day, every day, you’re not alone. And you’re not broken.

You deserve support that works. That’s gentle. That fits into your life without side effects or judgment. And affron® is one of those supports.

So whether you’re dealing with occasional anxious thoughts, restless nights, or you just want to feel more balanced and you again, consider giving Miss Bliss™ (and affron®) a spot in your daily routine.

Your mood matters. Your mental health matters. You matter.

1. https://www.apa.org/news/press/releases/stress/2010/gender-stress.pdf

2. https://www.fda.gov/consumers/womens-health-topics/women-and-anxiety

3. https://www.affronsaffron.com/about

4. https://www.affronsaffron.com/benefits

5. https://cdn.shopify.com/s/files/1/1241/4148/files/Affron_Brochure_04_2024_1.pdf?v=1746625386

6. https://www.ingredientsnetwork.com/mental-health-crisis-presents-challenges-and-news124436.html

7. https://www.gencorpacific.com/ingredients/affron

8. https://www.ncbi.nlm.nih.gov/books/NBK507250/

9. https://pmc.ncbi.nlm.nih.gov/articles/PMC6836118/